Books and Chapters of Books

 

Amorim BR, Okamura H, Yoshida K, Wang J, Qiu LH, Haneji T

The transcriptional factor Osterix directly interacts with RNA helicase A.

Oral Oncology, Vol. 12, Varma AK, Qiu WL, Zhang CP, Zhang ZY, eds,

Ocean Papers & Printers, New Delhi, pp. 216-222, 2008

 

 

Reviews

 

Okamura H, Haneji T

Role of transcription factors in multidrug resistance and apoptosis.

Dentistry in Japan, 43 (1), 1-6, 2007

 

岡村裕彦：口腔扁平上皮癌細胞の薬剤耐性とアポトーシス

~ 転写調節因子の役割 ~

四国歯学会雑誌, 19, 171-176, 2007

 

Okamura H, Yoshida K, Morimoto H, Teramachi J, Ochiai K, Haneji T, Yamamoto A

Role of protein phosphatase 2A in osteoblast differentiation.

Journal of Clinical Medicine, 6 (3), pii: E23, 2017 doi: 10.3390/jcm6030023.

 

Original Papers

 

2000-2010

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Morimoto Y, Morimoto H, Okamura H, Nomiyama K, Nakamuta N, Kobayashi S, Kito S, Ohba T, Haneji T.

Upregulation of the expression of Fas antigen and Fas ligand in a human submandibular gland ductal cell line by okadaic acid.

Archives of Oral Biology, 45 (8), 657-666, 2000

 

Morimoto Y, Kito S, Ohba T, Morimoto H, Okamura H, Haneji T.

Alteration of argyrophilic nucleolar organizer region associated (Ag-NOR) proteins in apoptosis-induced human salivary gland cells and human squamous carcinoma cells.

Journal of Oral Pathology and Medicine, 30 (4), 193-199, 2001

 

Okamura H, Morimoto H, Haneji T.

Peplomycin-induced apoptosis in oral squamous carcinoma cells depends on bleomycin sensitivity.

Oral Oncology, 37 (4), 379-385, 2001

 

Morimoto H, Okamura H, Haneji T.

Interaction of protein phosphatase 1 delta with nucleolin in osteoblastic cells.

Journal of Histochemistry and Cytochemistry, 50 (9), 1187-1193, 2002

 

Okamura H, Morimoto H, Fujita M, Nasu F, Sasaki E, Haneji T.

Suppression of Egr-1 expression in human oral squamous carcinoma cells by okadaic acid. Oral Oncology, 38 (8), 779-784, 2002

 

Kito S, Shimizu K, Okamura H, Yoshida K, Fujita M, Morimoto H, Morimoto Y, Ohba T, Haneji T.

Cleavage of nucleolin and argyrophilic nucleolar organizer region associated proteins in apoptosis-induced cells.

Biochemical and Biophysical Research Communications, 300 (4), 950-956, 2003

 

Yoshida K, Okamura H, Morimoto H, Nagata T, Haneji T.

Okadaic acid stimulates the receptor activator of nuclear factor-kappa B ligand (RANKL) in mouse osteoblastic cells.

Biomedical Research, 14 (2), 126-132, 2003

 

Sasaki E, Okamoto Y, Yoshida K, Okamura H, Shimizu K, Nasu F, Morimoto H, Haneji T.

Transblot and cytochemical identification of avidin-interacting proteins in mitochondria of cultured cells.

Histochemistry and Cell Biology, 120 (4), 327-333, 2003

 

Fujita M, Goto K, Yoshida K, Okamura H, Morimoto H, Kito S, Fukuda J, Haneji T.

Okadaic acid stimulates expression of Fas receptor and Fas ligand by activation of nuclear factor kappa-B in human oral squamous carcinoma cells.

Oral Oncology, 40 (2), 199-206, 2004

 

Okamura H, Yoshida K, Sasaki E, Morimoto H, Haneji T.

Transcription factor NF-Y regulates MDR1 expression through binding to inverted CCAAT sequence in drug-resistant human squamous carcinoma cells.

International Journal of Oncology, 25 (4), 1031-1037, 2004

 

Morimoto H, Okamura H, Yoshida K, Kitamura S, Haneji T.

Double-stranded RNA mediates selective gene silencing of protein phosphatase type 1 delta isoform in HEK-293 cells.

Journal of Enzyme Inhibition and Medical Chemistry, 19 (4), 327-331, 2004

 

Morimoto H, Okamura H, Yoshida K, Kitamura S, Haneji T.

Okadaic acid induces apoptosis through double-stranded RNA-dependent protein kinase/eukaryotic initiation factor-2α pathway in human osteoblastic MG63 cells.

Journal of Biochemistry, 136 (4), 433-438, 2004

 

岡村裕彦

薬剤耐性扁平上皮癌細胞におけるアポトーシスと転写調節因子

四国歯学会雑誌, 17 (1), 123-136, 2004

 

Okamura H, Yoshida K, Morimoto H, Haneji T.

PTEN expression elicited by Egr-1 transcription factor in calyculin A-induced apoptotic cells.

Journal of Cellular Biochemistry, 94 (1), 117-125, 2005

 

Morimoto H, Ozaki A, Okamura H, Yoshida K, Kitamura S, Haneji T.

Okadaic acid induces tyrosine phosphorylation of IkBa that mediated by PKR pathway in human osteoblastic MG63 cells.

Molecular and Cellular Biochemistry, 276 (1-2), 211-217, 2005

 

Yoshida K, Okamura H, Amorim BR, Ozaki A, Tanaka H, Morimoto H, Haneji T.

Double-stranded RNA-dependent protein kinase is required for bone calcification in MC3T3-E1 cells in vitro.

Experimental Cell Research, 311 (1), 117-125, 2005

 

Ozaki A, Morimoto H, Tanaka H, Okamura H, Yoshida K, Amorim BR, Haneji T.

Okadaic acid induces phosphorylation of p65NF-kB on serine 536 and activates NF-kB transcriptional activity in human osteoblastic MG63 cells.

Journal of Cellular Biochemistry, 99 (5), 1275-1284, 2006

 

Morimoto H, Ozaki A, Okamura H, Yoshida K, Amorim BR, Tanaka H, Kitamura S, Haneji T.

Differential expression of protein phosphatase type 1 isotypes and nucleolin during cell-cycle arrest.

Cell Biochemistry and Function, 25 (4), 369-375, 2007

 

Okamura H, Yoshida K, Sasaki E, Qiu LH, Amorim BR, Morimoto H, Haneji T.

Expression of PTEN and Akt phosphorylation in Lipopolysaccharide-treated NIH3T3 cells.

Cell Biology International, 31 (2), 119-125, 2007

 

Amorim BR, Okamura H, Yoshida K, Qiu LH, Morimoto H, Haneji T.

The transcriptional factor Osterix directly interacts with RNA helicase A.

Biochemical and Biophysical Research Communications, 355 (2), 347-351, 2007

 

Tanaka H, Yoshida K, Okamura H, Morimoto H, Nagata T, Haneji T.

Calyculin A induces apoptosis and stimulates phosphorylation of p65NF-kB in Human osteoblastic osteosarcoma MG63 cells.

International Journal of Oncology, 31 (2), 389-396, 2007

 

Akita K, Okamura H, Yoshida K, Morimoto H, Ogawa-Iyehara H, Haneji T.

Cobalt chloride induces apoptosis and zinc chloride suppresses cobalt-induced apoptosis by Bcl-2 expression in human submandibular gland HSG cells.

International Journal of Oncology, 31 (4), 923-929, 2007

 

Qiu LH, Yoshida K, Amorim BR, Okamura H, Haneji T.

Calyculin A stimulates the expression of TNF-a mRNA via phosphorylation of Akt in mouse osteoblastic MC3T3-E1 cells.

Molecular and Cellular Endocrinology, 271(1), 38-44, 2007

 

Okamura H, Yoshida K, Amorim BR, Haneji T.

Histone H1.2 is translocated to mitochondria and associates with Bak in bleomycin-induced apoptotic cells.

Journal of Cellular Biochemistry, 103 (5), 1488-1496, 2008

 

Okamura H, Amorim BR, Wang J, Yoshida K, Haneji T.

Calcineurin regulates phosphorylation status of transcription factor osterix.

Biochemical and Biophysical Research Communications, 379 (2), 440-444, 2009

 

Yoshida K, Okamura H, Amorim BR, Hinode D, Yoshida H, Haneji T.

PKR-mediated degradation of STAT1 regulates osteoblast differentiation.

Experimental Cell Research, 315 (12), 2105-2114, 2009

 

Okamura H, Yoshida K, Haneji T.

Negative regulation of TIMP1 is mediated by transcription factor TWIST.

International Journal of Oncology, 35 (1), 181-186, 2009

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2011-2015

 

Susilowati H, Okamura H, Hirota K, Shono M, Yoshida K, Murakami K, Tabata A, Nagamune H, Haneji T, Miyake Y.

Intermedilysin induces EGR-1 expression through calcineurin/NFAT pathway in human cholangiocellular carcinoma cells.

Biochemical and Biophysical Research Communications, 404 (1), 57-61, 2011

 

Okamura H, Yoshida K, Ochiai K, Haneji T.

Reduction of Protein Phosphatase 2A Cα enhances bone formation and osteoblast differentiation through the expression of bone-specific transcription factor Osterix.

Bone, 49 (3), 368-375, 2011

 

Yoshida K, Okamura H, Hoshino Y, Shono M, Yoshioka M, Hinode D, Yoshida H.

Interaction between PKR and PACT mediated by LPS-inducible NF-kB in human gingival cells.

Journal of Cellular Biochemistry, 113 (1), 165-173, 2012

 

Yoshida K, Okamura H, Ochiai K, Hoshino Y, Haneji T, Yoshioka M, Hinode D, Yoshida H.

PKR plays a positive role in osteoblast differentiation by regulating GSK-3b activity through a b-catenin-independent pathway.

Molecular and Cellular Endocrinology, 361 (1-2), 99-105, 2012

 

Okamura H, Yang D, Yoshida K, Haneji T.

Protein phosphatase 2A Cα is involved in osteoclastogenesis by regulating RANKL and OPG expression in osteoblasts.

FEBS Letters, 587 (1), 48-53, 2013

 

Okamura H, Yoshida K, Yang D, Haneji T.

Protein phosphatase 2A Cα regulates osteoblast differentiation and the expressions of bone sialoprotein and osteocalcin via osterix transcription factor.

Journal of Cellular Physiology, 228 (5), 1031-1037, 2013

 

Ishikawa M, Yoshida K, Okamura H, Ochiai K, Takamura H, Fujiwara N, Ozaki K.

Oral porphyromonas gingivalis translocates to the liver and regulates hepatic glycogen synthesis through the Akt/GSK-3β signalling pathway.

Biochimica Biophysica Acta-Molecular Basis of Disease, 1832 (12), 2035-2043, 2013

 

Yang D, Okamura H, Nakashima Y, Haneji T.

Histone demethylase Jmjd3 regulates osteoblast differentiation via transcription factors Runx2 and osterix.

Journal of Biological Chemistry, 288 (47), 33530-33541, 2013

 

Okamura H, Yang D, Yoshida K, Teramachi J, Haneji T.

Reduction of PP2A Cα stimulates adipogenesis by regulating the Wnt/GSK-3β/β-catenin pathway and PPARγ expression.

Biochimica Biophysica Acta-Molecular Cell Research, 1843 (11), 2376-2384, 2014

 

Guo J, Yang D, Okamura H, Teramachi J, Ochiai K, Qiu L, Haneji T.

Calcium hydroxide suppresses Porphyromonas endodontalis lipopolysaccharide-induced bone destruction.

Journal of Dental Research, 93 (5), 508-513, 2014

 

Yoshida K, Yoshioka M, Okamura H, Moriyama S, Kawazoe K, Grenier D, Hinode D.

Preventive effect of Daiokanzoto (TJ-84) on 5-fluorouracil-induced human gingival cell death through the inhibition of reactive oxygen species production.

PLoS One, 9 (11), e112689, 2014

 

Yu Y, Yang D, Qiu L, Okamura H, Guo J, Haneji T.

Tumor necrosis factor-α induces interleukin-34 expression through nuclear factor-kB activation in MC3T3-E1 osteoblastic cells.

Molecular Medicine Reports, 10 (3), 1371-1376, 2014

 

Shinohara H, Teramachi J, Okamura H, Yang D, Nagata T, Haneji T.

Double stranded RNA-dependent protein kinase is necessary for TNF-α-induced osteoclast formation in vitro and in vivo.

Journal of Cellular Biochemistry, 116 (9), 1957-1967, 2015

 

Yang D, Okamura H, Teramachi J, Haneji T.

Histone demethylase Utx regulates differentiation and mineralization in osteoblasts.

Journal of Cellular Biochemistry, 116 (11), 2628-2636, 2015

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2016-

 

Yang D, Okamura H, Teramachi J, Haneji T.

Histone demethylase Jmjd3 regulates osteoblast apoptosis through targeting anti-apoptotic protein Bcl-2 and pro-apoptotic protein Bim.

Biochimica Biophysica Acta-Molecular Cell Research, 1863 (4), 650-659, 2016.

 

Takamura H, Yoshida K, Okamura H, Fujiwara N, Ozaki K.

Porphyromonas gingivalis attenuates the insulin-induced phosphorylation and translocation of forkhead box protein O1 in human hepatocytes.

Archives Oral Biology, 69, 19-24, 2016

 

Yang D, Okamura H*, Morimoto H, Teramachi J, Haneji T.

Protein phosphatase 2A Cα regulates proliferation, migration, and metastasis of osteosarcoma cells.

Laboratory Investigation, 96(10), 1050-1062, 2016.

 

Teramachi J, Inagaki Y, Shinohara H, Okamura H, Yang D, Ochiai K, Baba R, Morimoto H, Nagata T, Haneji T.

PKR regulates LPS-induced osteoclast formation and bone destruction in vitro and in vivo.

Oral Disease, 23(2), 181-188, 2017.

 

Ma N, Yang D, Okamura H, Teramachi J, Hasegawa T, Qiu L, HanejiT.

Involvement of interleukin-23 induced by Porphyromonas endodontalis lipopolysaccharide in osteoclastogenesis.

Molecular Medicine Reports, 15 (2), 559-566, 2017

 

Yoshida K, Okamura H, Hiroshima Y, Abe K, Kido JI, Shinohara Y, Ozaki K.

PKR induces the expression of NLRP3 by regulating the NF-kB pathway in Porphyromonas gingivalis-infected osteoblasts.

Experimental Cell Research, 354(1), 57-64, 2017